Cancer Heterogeneity
and Immune Interactions

September 12-15, 2022

University Residential Center

Bertinoro (Forlì-Cesena), Italy


The Bertinoro Computational Biology (BCB) meeting, 2022, September 12-15, will focus on the topic of Cancer Heterogeneity and Immune Interactions and will be held in the small medieval hilltop town of Bertinoro, see pictures and map. It is a small workshop with around 40 participants and it can be viewed as a continuation of earlier successful BCB meetings on Computational Cancer Research. 


As the field of immuno-oncology gains in importance following in the success of checkpoint blockade inhibitors, increasing focus must be placed on understanding the interaction between malignant cells and patients' immune responses.

Moreover, measurement technologies capable of surveying the entire 'ecosystem' of cells comprising a tumor such as single cell sequencing and in situ multiplexed imaging methods have become stable and robust for quantitative profiling of the tumor microenvironment (TME). Consequently, computational and statistical methods must be advanced in order to maximize biological interpretability with statistical and quantitative rigor. Our meeting will focus on computational methods development, application of measurement technologies and biological interpretation of immune-malignant cell interaction and cancer evolution in the context of the TME. 


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